Abstract:With the scale and extensive use of the data and information processing, big data has become a strong support for audit projects, which has improved the audit efficiency. The “big data audit era” is coming. For the recent several years, the audit projects of GuiZhou Power Grid Limited Company have gained remarkable achievements in scope, requirement and measure. Especially the big data technology is used in the economic responsibility audit projects. The development of economic responsibility audit project exposes the problems existing in the operation and management of the company''s units at all levels, and puts forward reasonable suggestions for management improvement, which provides a very meaningful decision-making reference for the company''s management. Based on the analysis of the results of economic responsibility audit project of GuiZhou Power Grid Limited Company in recent years, and the summary of the application of data technology, this paper reflects on the shortcomings in the process of project management, and guides how to further promote the smooth and efficient development of economic responsibility audit through the big data platform, and continue to give full play to internal audit supervision-the role of eyes.